The transformation of multifunctional bio-patch to hydrogel on skin wounds for efficient scarless wound healing.

ABSTRACT: Hydrogels have been widely used in various biomedical applications, including skin regeneration and tissue repair. However, the capability of certain hydrogels to absorb exudate or blood from surrounding wounds, coupled with the challenge in their long-term storage to prevent bacterial growth, can pose limitations to their efficacy in biological applications. To address these challenges, the development of a multifunctional aloin-arginine-alginate (short for 3A) bio-patch capable of transforming into a hydrogel upon absorbing exudate or blood from neighboring wounds for cutaneous regeneration is proposed. The 3A bio-patch exhibits outstanding features, including an excellent porous structure, swelling properties, and biodegradability. These characteristics allow for the rapid absorption of

SUBMITTER: Ying X 

PROVIDER: S-EPMC10770564 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature