Frequency of cardiotoxicity following intramuscular administration of epinephrine in emergency department patients with anaphylaxis.

ABSTRACT:

Objectives

Epinephrine can be a life-saving treatment for patients with anaphylaxis. Potential cardiovascular side effects of epinephrine may contribute to clinician hesitancy to use it. However, the frequency of cardiotoxicity resulting from epinephrine treatment for anaphylaxis is not well described. We sought to describe the frequency of cardiotoxicity following intramuscular (IM) administration of epinephrine in adult emergency department (ED) patients with anaphylaxis.

Methods

We conducted a retrospective observational study at a single, quaternary care academic ED in Tennessee. We identified consecutive ED visits with the diagnosis of anaphylaxis from 2017 to 2021 who received at least one intramuscular (IM) dose of epinephrine in the ED. Analysis was primarily descrip

SUBMITTER: Pauw EK 

PROVIDER: S-EPMC10771040 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature