Motor symptoms of Parkinson's disease are affected by temperature: A controlled pilot study.

ABSTRACT:

Purpose

The motor symptoms (MS) of Parkinson's disease (PD) have been affecting the quality of life in patients. In clinical practice, most patients with PD report that MS are more severe in winter than in summer, and hyperthermic baths (HTB) could temporarily improve MS. The study aimed to evaluate the effects of seasonal variation and aquatic thermal environment of HTB on the MS of PD.

Patients and methods

A cross-sectional study of 203 Chinese Han patients was performed. Univariate and multivariate analyses were performed to analyze seasonal variation in MS relative to baseline data (sex, age at onset, duration, season of birth, Hoehn and Yahr stage, family history, levodopa equivalent dose, and the effect of HTB on MS). Ten subjects participated in the HTB study, and one

SUBMITTER: Huang T 

PROVIDER: S-EPMC10771231 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature