Sympathetic nerve blocks for posttraumatic stress disorder: an evidentiary review for future clinical trials.

ABSTRACT: Posttraumatic stress disorder (PTSD) is a chronic disorder resulting from exposure to traumatic events. In recent years, sympathetic nerve blocks have gained interest as an emerging treatment modality for PTSD. They have been shown to reduce autonomic dysfunction associated with PTSD symptoms, particularly in refractory and treatment-resistant patients. However, there is limited evidence regarding the technique's effectiveness in PTSD patients. Therefore, this scoping review was designed to update and summarize the current literature on this topic to inform the design of future clinical trials and studies. Our review of 22 studies (mostly case reports and series) included 1,293 PTSD patients who received sympathetic nerve blocks, primarily military service members and veterans, with a medi

SUBMITTER: Prasad S 

PROVIDER: S-EPMC10771322 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature