Analysing potent biomarkers along phytochemicals for breast cancer therapy: an in silico approach.

ABSTRACT:

Purpose

This research focused on the identification of herbal compounds as potential anti-cancer drugs, especially for breast cancer, that involved the recognition of Notch downstream targets NOTCH proteins (1-4) specifically expressed in breast tumours as biomarkers for prognosis, along with P53 tumour antigens, that were used as comparisons to check the sensitivity of the herbal bio-compounds.

Methods

After investigating phytochemical candidates, we employed an approach for computer-aided drug design and analysis to find strong breast cancer inhibitors. The present study utilized in silico analyses and protein docking techniques to characterize and rank selected bio-compounds for their efficiency in oncogenic inhibition for use in precise carcinomic cell growth control.

SUBMITTER: Shekar N 

PROVIDER: S-EPMC10771382 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature