Non-contrast ultrasound image analysis for spatial and temporal distribution of blood flow after spinal cord injury.

ABSTRACT: Ultrasound technology can provide high-resolution imaging of blood flow following spinal cord injury (SCI). Blood flow imaging may improve critical care management of SCI, yet its duration is limited clinically by the amount of contrast agent injection required for high-resolution, continuous monitoring. In this study, we aim to establish non-contrast ultrasound as a clinically translatable imaging technique for spinal cord blood flow via comparison to contrast-based methods and by measuring the spatial distribution of blood flow after SCI. A rodent model of contusion SCI at the T12 spinal level was carried out using three different impact forces. We compared images of spinal cord blood flow taken using both non-contrast and contrast-enhanced ultrasound. Subsequently, we processed the imag

SUBMITTER: Routkevitch D 

PROVIDER: S-EPMC10771432 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature