Do patients with cN0 oral squamous cell carcinoma benefit from elective neck dissection? A large-scale population-based study.

ABSTRACT:

Background

The neck management of clinical-nodal negative (cN0) oral squamous cell carcinoma (OSCC) remains controversial. Elective neck dissection (END) and observation are the main strategies, but it is still not clear who could benefit the most from END. The purpose of this study was to clarify the potential clinical factors that affect the therapeutic value of END and to explore the actual characteristics associated with benefit from END.

Methods

Patients with cN0 OSCC were identified in the SEER database from 2000 to 2019. 5-year Overall survival (OS) and disease-specific survival (DSS) were analyzed using the Kaplan‒Meier method, and the hazard ratios (HRs) for survival were estimated using the Cox regression model. Multiple subgroup analyses of DSS and OS among differ

SUBMITTER: Wu Q 

PROVIDER: S-EPMC10771637 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature