Polysubstance mortality trends in White and Black Americans during the opioid epidemic, 1999-2018.

ABSTRACT:

Background

Psychoactive drug combinations are increasingly contributing to overdose deaths among White and Black Americans. To understand the evolving nature of overdose crisis, inform policies, and develop tailored and equitable interventions, this study provides a comprehensive assessment of polysubstance mortality trends by race and sex during the opioid epidemic.

Methods

We used serial cross-sectional US mortality data for White and Black populations from 1999 through 2018 to calculate annual age-adjusted death rates (AADR) involving any opioid, opioid subtypes, benzodiazepines, cocaine, psychostimulants, or combinations of these drugs, stratified by race and sex. Trend changes in AADR were analyzed using joinpoint regression models and expressed as average annual percen

SUBMITTER: Rawy M 

PROVIDER: S-EPMC10771660 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature