Prevalence, trend, and associated risk factors for cleft lip with/without cleft palate: a national study on live births from 2016 to 2021.

ABSTRACT:

Backgrounds

Cleft lip with or without cleft palate (CL/P) is the most common congenital craniofacial anomaly, including non-syndromic cleft lip with or without cleft palate and cleft palate only. Failure in the fusion of median and lateral nasal processes, the maxillary prominence, and soft tissues around the oral cavity can cause CL/P. Previously, the prevalence has been estimated to be 1 among every 1000 births in 2014 among American neonates and no other reports have been available since. Thus, this study aimed to calculate the prevalence and trend of isolated CL/P among American live births from 2016 to 2021 with its associated risk factors.

Methods and materials

In this cross-sectional population-based retrospective study, we used live birth data provided by the Nationa

SUBMITTER: Heydari MH 

PROVIDER: S-EPMC10771673 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature