Risk perception and intended behavior change after uninformative genetic results for adult-onset hereditary conditions in unselected patients.

ABSTRACT: Population genetic screening for preventable adult-onset hereditary conditions may improve disease management and morbidity but most individuals will receive uninformative results that do not indicate higher risk for disease. Investigation into subsequent psychosocial health and behaviors is necessary to inform population screening feasibility, effectiveness, and cost considerations. We conducted a prospective survey study of unselected University of Washington Medicine patients enrolled in a genetic research study screening for pathogenic variation in medically important genes. Survey questions adapted from the Feelings About genomiC Testing Results (FACToR) questionnaire and designed to understand perceived disease risk change and planned health behaviors were administered after receipt

SUBMITTER: Rao ND 

PROVIDER: S-EPMC10772064 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature