Sotrovimab in solid organ transplant recipients with COVID-19: a systematic review and meta-analysis.

ABSTRACT:

Background

Despite widespread implementation of vaccination against coronavirus disease 2019 (COVID-19), solid organ transplant recipients (SOTRs) can remain particularly vulnerable to this disease. The present study was conducted to investigate the efficacy and safety of sotrovimab in the treatment of SOTRs with COVID-19.

Methods

A search was performed of PubMed, Cochrane Library, Web of Science, medRxiv, and Google Scholar to gather relevant evidence through July 25, 2023. The quality of the included studies was assessed using the risk of bias tool. Comprehensive Meta-Analysis software (ver. 3.0, Biostat) was employed for data analysis.

Results

Ten studies, involving a total of 1,569 patients, were included. The meta-analysis revealed significant differences between

SUBMITTER: Amani B 

PROVIDER: S-EPMC10772269 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature