Patient-Reported Outcomes Measures, Polycystic Kidney Disease Burden, and Outcomes in Autosomal Dominant Polycystic Kidney Disease.

ABSTRACT:

Rationale & objective

Using OVERTURE (NCT01430494) study data on patient-perceived health, health care utilization, and productivity in autosomal dominant polycystic kidney disease (ADPKD), this research was conducted to characterize the burden of illness in patients with ADPKD and assess whether patient-reported outcome (PRO) assessment scores predict clinical and health-economic outcomes.

Study design

Data were analyzed from a prospective, observational study.

Setting & participants

The study cohort comprised 3,409 individuals with ADPKD in 20 countries who were aged 12-78 years and were in chronic kidney disease (CKD) stages G1-G5 and Mayo risk subclasses 1A-1E.

Predictors

Scores on PRO instruments, including disease-specific assessments [ADPKD-Impact Scale

SUBMITTER: Oberdhan D 

PROVIDER: S-EPMC10772284 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature