Brain MRI changes in degenerative cervical myelopathy: a systematic review.

ABSTRACT:

Background

Degenerative cervical myelopathy (DCM) is the most common cause of adult spinal cord dysfunction globally. Associated neurological symptoms and signs have historically been explained by pathobiology within the cervical spine. However, recent advances in imaging have shed light on numerous brain changes in patients with DCM, and it is hypothesised that these changes contribute to DCM pathogenesis. The aetiology, significance, and distribution of these supraspinal changes is currently unknown. The objective was therefore to synthesise all current evidence on brain changes in DCM.

Methods

A systematic review was performed. Cross-sectional and longitudinal studies with magnetic resonance imaging on a cohort of patients with DCM were eligible. PRISMA guidelines were fo

SUBMITTER: Rafati Fard A 

PROVIDER: S-EPMC10772405 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature