Impact of CT-guided hookwire localization on tumor spread through air spaces in stage IA lung adenocarcinoma.

ABSTRACT:

Background

It remains undetermined whether preoperative computed tomography (CT)-guided hookwire localization would result in elevated risk of tumor spread through air spaces (STAS) in stage IA lung adenocarcinoma.

Methods

A total of 1836 patients who underwent lobectomy were included. To eliminate the potential impact of confounding factors on producing STAS, propensity score-matching (PSM) was used to create two balanced subgroups stratified by implementation of hookwire localization. We also introduced an external cohort including 1486 patients to explore the effect of hookwire localization on the incidence of STAS and patient survival after sublobar resection (SR). For proactive simulation of hookwire localization, 20 consecutive lobectomy specimens of p-stage IA lung ad

SUBMITTER: Wang X 

PROVIDER: S-EPMC10772635 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature