TLR3 Gene Polymorphism in HCV Infection in the Kazakh Population of Western Kazakhstan.

ABSTRACT:

Background and objectives

Hepatitis C virus (HCV) infection is a common cause of cirrhosis worldwide, leading to significant economic and social burdens. Approximately 170 million people (3% of the population) are infected with HCV, with the risk of developing complications such as cirrhosis and hepatocellular carcinoma. In the United States, HCV is the main cause of liver cirrhosis, accounting for 26% of cases. Recent studies have shown an increase in the proportion of HCV-related liver cirrhosis.

Materials and methods

A total of 102 patients with chronic hepatitis C in the reactivation phase from the Atyrau and Aktobe regional hepatology centers, who had not previously received antiviral therapy, were examined. A control group, matched by gender and age, included 127 pract

SUBMITTER: Nurlanova G 

PROVIDER: S-EPMC10772782 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature