Vaccine-induced immune thrombotic thrombocytopenia post COVID-19 booster vaccination in Brazil: a case series.

ABSTRACT:

Background

The emergence of new variants of SARS-CoV-2 has led to the administration of different booster vaccines to mitigate COVID-19. Vaccines with adenoviral vectors have been rarely associated with vaccine-induced immune thrombotic thrombocytopenia (VITT).

Objectives

This study aimed to describe 15 cases of VITT after the third and fourth doses of the COVID-19 vaccine in Brazil.

Methods

Cases were reported after all kinds of anti-SARS-CoV-2 booster vaccinations between October 17, 2021, and September 4, 2022.

Results

Of the 26 suspected cases, 15 cases of VITT were analyzed. Of these, 10 were classified as definite VITT, 2 as probable, 1 as possible, and 2 as unlikely. The estimated frequency of definite, probable, or possible VITT was 0.33 cases per milli

SUBMITTER: Mendes-de-Almeida DP 

PROVIDER: S-EPMC10772875 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature