Mechanically assisted cough strategies: user perspectives and cough flows in children with neurodisability.

ABSTRACT:

Background

Mechanical insufflation-exsufflation (MI-E) is used to augment cough in children with neurodisability. We aimed to determine the user comfort and cough flows during three MI-E strategies, and to predict factors associated with improved comfort and cough flows.

Methods

This multicentre, crossover trial was done at four regional hospitals in Norway. Children with neurodisability using MI-E long term via mask were enrolled. In randomised order, they tested three MI-E setting strategies (in-/exsufflation pressure (cmH₂O)/in (In)- versus exsufflation (Ex) time): 1) "A-symmetric" (±50/In=Ex); 2) "B-asymmetric" (+25- +30)/-40, In>Ex); and 3) "C-personalised", as set by their therapist. The primary outcomes were user-reported comfort on a visual a

SUBMITTER: Hov B 

PROVIDER: S-EPMC10772903 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature