Retinal Vascular Measurements and Mortality Risk: Evidence From the UK Biobank Study.

ABSTRACT:

Purpose

This study aimed to investigate the association between quantitative retinal vascular measurements and the risk of all-cause and premature mortality.

Methods

In this population-based cohort study using the UK Biobank data, we employed the Retina-based Microvascular Health Assessment System to assess fundus images for image quality and extracted 392 retinal vascular measurements per fundus image. These measurements encompass six categories of vascular features: caliber, density, length, tortuosity, branching angle, and complexity. Univariate Cox regression models were used to identify potential indicators of mortality risk using data on all-cause and premature mortality from death registries. Multivariate Cox regression models were then used to test these associations

SUBMITTER: Yusufu M 

PROVIDER: S-EPMC10773151 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature