Brain morphological variability between whites and African Americans: the importance of racial identity in brain imaging research.

ABSTRACT: In a segregated society, marked by a historical background of inequalities, there is a consistent under-representation of ethnic and racial minorities in biomedical research, causing disparities in understanding genetic and acquired diseases as well as in the effectiveness of clinical treatments affecting different groups. The repeated inclusion of small and non-representative samples of the population in neuroimaging research has led to generalization bias in the morphological characterization of the human brain. A few brain morphometric studies between Whites and African Americans have reported differences in orbitofrontal volumetry and insula cortical thickness. Nevertheless, these studies are mostly conducted in small samples and populations with cognitive impairment. For this reason,

SUBMITTER: Atilano-Barbosa D 

PROVIDER: S-EPMC10773238 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature