Pain and Its Association with Survival for Black and White Individuals with Advanced Prostate Cancer in the United States.

ABSTRACT: Bone pain is a well-known quality-of-life detriment for individuals with prostate cancer and is associated with survival. This study expands previous work into racial differences in multiple patient-reported dimensions of pain and the association between baseline and longitudinal pain and mortality. This is a prospective cohort study of individuals with newly diagnosed advanced prostate cancer enrolled in the International Registry for Men with Advanced Prostate Cancer (IRONMAN) from 2017 to 2023 at U.S. sites. Differences in four pain scores at study enrollment by race were investigated. Cox proportional hazards models and joint longitudinal survival models were fit for each of the scale scores to estimate HRs and 95% confidence intervals (CI) for the association with all-cause mortality.

SUBMITTER: Rencsok EM 

PROVIDER: S-EPMC10773321 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature