Multicentre external validation of the prognostic model kidney failure risk equation in patients with CKD stages 3 and 4 in Peru: a retrospective cohort study.

ABSTRACT:

Objectives

To externally validate the four-variable kidney failure risk equation (KFRE) in the Peruvian population for predicting kidney failure at 2 and 5 years.

Design

A retrospective cohort study.

Setting

17 primary care centres from the Health's Social Security of Peru.

Participants

Patients older than 18 years, diagnosed with chronic kidney disease stage 3a-3b-4 and 3b-4, between January 2013 and December 2017. Patients were followed until they developed kidney failure, died, were lost, or ended the study (31 December 2019), whichever came first.

Primary and secondary outcome measures

Performance of the KFRE model was assessed based on discrimination and calibration measures considering the competing risk of death.

Results

We included 7519 pa

SUBMITTER: Bravo-Zuniga J 

PROVIDER: S-EPMC10773413 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature