Incidence of interstitial lung abnormalities: the MESA Lung Study.

ABSTRACT:

Background

The incidence of newly developed interstitial lung abnormalities (ILA) and fibrotic ILA has not been previously reported.

Methods

Trained thoracic radiologists evaluated 13 944 cardiac computed tomography scans for the presence of ILA in 6197 Multi-Ethnic Study of Atherosclerosis (MESA) longitudinal cohort study participants >45 years of age from 2000 to 2012. Five percent of the scans were re-read by the same or a different observer in a blinded fashion. After exclusion of participants with ILA at baseline, incidence rates and incidence rate ratios for ILA and fibrotic ILA were calculated.

Results

The intra-reader agreement of ILA was 92.0% (Gwet's AC1 0.912, intraclass correlation coefficient (ICC) 0.982) and the inter-reader agreement of ILA was 83.5% (G

SUBMITTER: McGroder CF 

PROVIDER: S-EPMC10773573 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature