Effects of tumour budding on adjuvant chemotherapy in colorectal cancer.

ABSTRACT:

Background

High tumour budding has been indicated as a risk factor of poor survival in colorectal cancer. This study aimed to investigate the impact of tumour budding grades and the use of adjuvant chemotherapy on prognosis in patients with colorectal cancer.

Methods

This study included consecutive colorectal cancer patients who underwent radical surgery for primary colorectal adenocarcinoma at The Sixth Hospital of Sun Yat-sen University between 2009 and 2019. Tumour budding was assessed based on the recommendations of the International Tumor Budding Consensus Conference using haematoxylin and eosin (H&E)-stained slides with tumour samples. The primary outcome of interest was to correlate tumour budding with disease-free survival and overall survival; the secondary outcome

SUBMITTER: Xie H 

PROVIDER: S-EPMC10773627 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature