Defining oligometastatic pancreatic cancer: a systematic review and critical synthesis of consensus.

ABSTRACT:

Background

Small retrospective series suggest that local consolidative treatment (LCT) may improve survival in oligometastatic pancreatic ductal adenocarcinoma (PDAC). However, no uniform definition of oligometastatic disease (OMD) in PDAC exists; this impedes meaningful conclusions.

Patients and methods

A systematic literature search using PubMed, Web of Science, and Cochrane CENTRAL registries for studies and protocols reporting on definitions and/or LCT of OMD in PDAC was performed. The primary endpoint was the definition of OMD. Levels of agreement were categorized as consensus (≥75% agreement between studies), fair agreement (50%-74%), and absent/poor agreement (<50%).

Results

After screening of 5374 abstracts, the full text of 218 studies was assessed, of which

SUBMITTER: Leonhardt CS 

PROVIDER: S-EPMC10774968 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature