Chronic fatigue in childhood cancer survivors is associated with lifestyle and psychosocial factors; a DCCSS LATER study.

ABSTRACT:

Background

The purpose of this study was to determine factors associated with chronic fatigue (CF) in childhood cancer survivors (CCS).

Patients and methods

Participants were included from the Dutch Childhood Cancer Survivor Study (DCCSS) LATER cohort, a nationwide cohort of CCS (≥5 years after diagnosis) and siblings as controls. Fatigue severity was assessed with the 'fatigue severity subscale' of the Checklist Individual Strength ('CIS-fatigue'). CF was defined as scoring ≥35 on the 'CIS-fatigue' and having fatigue symptoms for ≥6 months. Twenty-four parameters were assessed, categorized into assumed fatigue triggering, maintaining and moderating factors. Multivariable logistic regression analyses were carried out to investigate the association of these factors with CF.

SUBMITTER: Penson A 

PROVIDER: S-EPMC10774970 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature