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ABSTRACT: Importance
Publishing study protocols might reduce research waste because of unclear methods or incomplete reporting; on the other hand, there might be few additional benefits of publishing protocols for registered trials that are never completed or published. No study has investigated the proportion of published protocols associated with published results.Objective
To estimate the proportion of published trial protocols for which there are not associated published results.Design, setting, and participants
This cross-sectional study used stratified random sampling to identify registered clinical trials with protocols published between January 2011 and August 2022 and indexed in PubMed Central. Ongoing studies and those within 1 year of the primary completion date on
SUBMITTER: Vorland CJ
PROVIDER: S-EPMC10774993 | biostudies-literature | 2024 Jan
REPOSITORIES: biostudies-literature