The robustness of the flow-gradient classification of severe aortic stenosis.

ABSTRACT:

Objectives

A flow-gradient classification is used to determine the indication for intervention for patients with severe aortic stenosis (AS) with discordant echocardiographic parameters. We investigated the agreement in flow-gradient classification by stroke volume (SV) measurement at the left ventricular outflow tract (LVOT) and at the left ventricle.

Methods

Data were used from a prospective cohort study and patients with severe AS (aortic valve area index ≤0.6 cm²/m²) with preserved ejection fraction (>50%) were selected. SV was determined by an echocardiographic core laboratory at the LVOT and by subtracting the 2-dimensional left ventricle end-systolic from the end-diastolic volume (volumetric). Patients were stratified into 4 groups based on SV in

SUBMITTER: Velders BJJ 

PROVIDER: S-EPMC10775038 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature