Changes in Body Composition Before and After Parkinson's Disease Diagnosis.

ABSTRACT:

Background

Weight loss is common in Parkinson's disease (PD). However, little is known about when it starts, how PD changes as it progresses, and whether there is a differential loss of lean or fat mass. The objective of this study was to examine how body composition changes before and after PD diagnosis.

Methods

In the Health, Aging, and Body Composition study (n = 3075; age range, 70-79 years), body composition was assessed using dual-energy x-ray absorptiometry on an annual or biennial basis from year 1 to year 10. For each PD case each year, we calculated the difference between their actual body composition measures and expected values had they not developed PD. Using linear mixed models with crossed random effects, we further examined the trend of change in body composi

SUBMITTER: Song S 

PROVIDER: S-EPMC10775470 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature