Low plasma vitamin D is associated with increased 28-day mortality and worse clinical outcomes in critically ill patients.

ABSTRACT:

Background & objective

Patients in the intensive care unit have a high prevalence of vitamin D deficiency (VDD). In the present study, clinical outcomes in the ICU were analyzed with vitamin D status.

Materials and methods

In this prospective, multicenter study, sampling was conducted on seven ICUs in three hospitals. Within the first 24 h of ICU admission, patient's serum vitamin D levels were measured, and their disease severity was monitored using the scores of acute physiologic assessment and chronic health evaluation II (APACHE II), sequential organ failure assessment (SOFA), and the modified Nutrition Risk in Critically ill (mNUTRIC) score.

Results

A total of 236 patients were enrolled in this study, of which 163 (69.1%) had lower vitamin D levels than 20 ng/ml

SUBMITTER: Sistanian F 

PROVIDER: S-EPMC10775546 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature