PCV-VG combined individualized PEEP determination in one-lung ventilated patients with PEEP step change direction: A randomized controlled trial.

ABSTRACT:

Introduction

The efficacy of pressure-controlled volume-guaranteed ventilation (PCV-VG) combined with a gradient-directional change in positive end-expiratory pressure (PEEP) during one-lung ventilation (OLV) in patients who underwent thoracoscopic surgery was investigated.

Methods

Ninety patients were randomly divided into the PC (PCV-VG + 5 cm H₂ O fixed PEEP), PI (PCV-VG + incremental PEEP titration), and PD (PCV-VG + decremental PEEP titration) groups. Hemodynamic (heart rate [HR] and mean arterial pressure [MAP]), respiratory mechanics (P_peak , P_mean, and Cdyn), and arterial blood gas (pH, PaCO₂ , PaO₂ , and PaO₂ /FiO₂ ) indices were evaluated at T₁ (10 min of two-lung ventilation [T

SUBMITTER: Li G 

PROVIDER: S-EPMC10775886 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature