A novel twin-grasper assisted mucosal inverted closure technique for closing large artificial gastric mucosal defects.

ABSTRACT:

Background

Large artificial gastric mucosal defects are always left unclosed for natural healing due to technique difficulties in closure. This study aims to evaluate the feasibility and safety of a new Twin-grasper Assisted Mucosal Inverted Closure (TAMIC) technique in closing large artificial gastric mucosal defects.

Methods

Endoscopic submucosal dissection (ESD) was performed in fifteen pigs to create large gastric mucosal defects. The mucosal defects were then either left unclosed or closed with metallic clips using TAMIC technique. Successful closure rate and the wound outcomes were assessed.

Results

Two mucosal defects with size of about 4.0 cm were left unclosed and healed two months after surgery. Thirteen large gastric mucosal defects were created by ESD with

SUBMITTER: Cai Q 

PROVIDER: S-EPMC10776692 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature