Poor functional status at the time of waitlist for pediatric lung transplant is associated with worse pretransplant outcomes.

ABSTRACT:

Background

Whether functional status is associated with survival to pediatric lung transplant is unknown. We hypothesized that completely dependent functional status at waitlist registration, defined using Lansky Play Performance Scale (LPPS), would be associated with worse outcomes.

Methods

Retrospective cohort study of pediatric lung transplant registrants utilizing United Network for Organ Sharing's Standard Transplant Analysis and Research files (2005-2020). Primary exposure was completely dependent functional status, defined as LPPS score of 10-40. Primary outcome was waitlist removal for death/deterioration with cause-specific hazard ratio (CSHR) regression. Subdistribution hazard regression (SHR, Fine and Gray) was used for the secondary outcome of waitlist removal du

SUBMITTER: Himebauch AS 

PROVIDER: S-EPMC10776805 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature