Gastrointestinal distress as a potential mediator between stress and periodontal inflammation.

ABSTRACT:

Objectives

Periodontal disease is multifactorial in its aetiology, which encompasses biopsychosocial contributors, including psychological stress. Gastrointestinal distress and dysbiosis have been associated with several chronic inflammatory diseases yet have rarely been investigated with respect to oral inflammation. Given the implications of gastrointestinal distress on extraintestinal inflammation, this study aimed to evaluate the potential role of such distress as a mediator between psychological stress and periodontal disease.

Methods

Utilizing a cross-sectional, nationwide sample of 828 adults in the USA generated via Amazon Mechanical Turk, we evaluated data collected from a series of validated self-report psychosocial questionnaires on stress, gut-specific anxiety ar

SUBMITTER: Wright CD 

PROVIDER: S-EPMC10776810 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature