Comparative before-after study of fever prevention versus targeted temperature management following out-of-hospital cardiac arrest.

ABSTRACT:

Background

International guidelines for neuroprotection following out-of-hospital cardiac arrest (OHCA) recommend fever prevention ahead of routine temperature management. This study aimed to identify any effect of changing from targeted temperature management to fever prevention on neurological outcome following OHCA.

Methods

A retrospective observational cohort study was conducted of consecutive admissions to an ICU at a tertiary OHCA centre. Comparison was made between a period of protocolised targeted temperature management (TTM) to 36 °C and a period of fever prevention.

Results

Data were available for 183 patients. Active temperature management was administered in 86/118 (72%) of the TTM cohort and 20/65 (31%) of the fever prevention group. The median highest te

SUBMITTER: Leadbeater P 

PROVIDER: S-EPMC10776978 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature