Investigating outlier rates of cardiac troponin I and troponin T assays: A systematic review.

ABSTRACT:

Objectives

This review aimed to harmoniously summarize and compare outlier rates for various cardiac troponin (cTn) assays, including high-sensitivity-cTn (hs-cTn) assays and contemporary cTn (generation of assays prior to hs-cTn ones) assays, from the published studies.

Methods

The PRISMA guidelines were utilized to perform this systematic review. Five databases, including PubMed, Scopus, Embase, Cochrane Library, and Web of Science, were searched using specific keywords up to June 30th, 2023. Studies reporting specifically calculated outlier rates for cTn assays when conducting in-vitro diagnosis in human samples were included. Selected studies were then further assessed using the GRADE tool.

Results

Thirteen studies were included. The data from the studies were sum

SUBMITTER: Zhang L 

PROVIDER: S-EPMC10776999 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature