Chemical prophylaxis and venous thromboembolism following elective spinal surgery: A systematic review and meta-analysis.

ABSTRACT:

Background

Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is a potentially devastating complication after surgery. Spine surgery is associated with an increased risk of postoperative bleeding, such as spinal epidural hematomas (SEH), which complicates the use of anticoagulation. Despite this dilemma, there is a lack of consensus around perioperative VTE prophylaxis. This systematic review investigates the relationship between chemoprophylaxis and the incidence rates of VTE and SEH in the elective spine surgical population.

Methods

A comprehensive literature search was performed using PubMed, Embase, and Cochrane databases to identify studies published after 2,000 that compared VTE chemoprophylaxis use in elective spine surgery

SUBMITTER: Rahmani R 

PROVIDER: S-EPMC10777073 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature