Obesity, Twin Pregnancy, and the Role of Assisted Reproductive Technology.

ABSTRACT:

Importance

The prevalence of overweight and obesity (body mass index [BMI] ≥25) has increased globally, and high BMI has been linked to higher rates of twin birth. However, evidence from large population-based studies is lacking; the issue needs careful study, as women with obesity are also more likely to use assisted reproductive technology (ART), which frequently results in twin pregnancy.

Objective

To examine the association between BMI and twin birth and the role of ART as a potential mediator in this association.

Design, setting, and participants

This retrospective cohort study included all live births and stillbirths with gestational age of 20 weeks or longer in British Columbia, Canada, from 2008 to 2020, using data from the British Columbia Perinatal Database

SUBMITTER: Bone JN 

PROVIDER: S-EPMC10777255 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature