Integrated Bioinformatic Analysis of Differentially Expressed Genes Associated with Wound Healing.

ABSTRACT:

Objective

Wound healing is a complex process involving the coordinated interaction of various genes and molecular
pathways. The study aimed to uncover novel therapeutic targets, biomarkers and candidate genes for drug development
to improve successful wound repair interventions.
Materials and Methods: This study is a network-meta analysis study. Nine wound healing microarray datasets obtained
from the Gene Expression Omnibus (GEO) database were used for this study. Differentially expressed genes (DEGs)
were described using the Limma package and shared genes were used as input for weighted gene co-expression
network analysis. The Gene Ontology analysis was performed using the EnrichR web server, and construction of a
protein-protein interaction (PP

SUBMITTER: Farhangniya M 

PROVIDER: S-EPMC10777322 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature