The association between bilirubin levels, and the incidence of metabolic syndrome and diabetes mellitus: a systematic review and meta-analysis of cohort studies.

ABSTRACT:

Objectives

The objective of this meta-analysis was to investigate the association between plasma bilirubin levels and the incidence of metabolic syndrome and diabetes mellitus across all populations.

Methods

Several databases were searched, including PubMed (Medline), Scopus, Web of Science, and Embase (Elsevier), to identify relevant cohort studies. All cohort studies that reported the risk ratio along with a 95% confidence interval were included. The association between bilirubin levels and metabolic syndrome or diabetes was reported as a pooled RR with a 95% CI in the forest plot. All analyses were conducted using STATA version 17, with a significance level of 0.05.

Results

Out of the 10 studies included in the analysis, four investigated the effect of hyperbilirub

SUBMITTER: Nikouei M 

PROVIDER: S-EPMC10777508 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature