Association of polymorphism of IL-17A, IL-17F, and IL-6 with Toxoplasma gondii infection susceptibility in HIV/AIDS patients in Shiraz, southern Iran.

ABSTRACT:

Introduction

Toxoplasma gondii infection is considered as one of the most important opportunistic infections and cause of death in HIV patients.

Methods

In this cross-sectional study, 334 HIV positive patients were included. The molecular test was performed by the restriction fragment length polymorphism-polymerase chain reaction method. Allelic frequency, haplotype analyses, and linkage disequilibrium were calculated. The odds ratio was calculated. The linear regression model was used to analysis of interleukin (IL)-17A, IL-17F, and IL-6 single-nucleotide polymorphism genotypes in HIV patients with and without toxoplasmosis.

Results

In total, 95 tested'patients (28.4%) were positive for toxoplasmosis. The risk of toxoplasma infection in the current study did not corr

SUBMITTER: Nejabat M 

PROVIDER: S-EPMC10777877 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature