Interaction between long noncoding RNA and microRNA in lung inflammatory diseases.

ABSTRACT:

Background

Non-coding RNAs (ncRNAs) are a group of RNAs that cannot synthesize proteins, but are critical in gene expression regulation. Long non-coding RNAs (lncRNAs) and microRNAs (miRNAs), the two major family members, are intimately involved in controlling immune response, cell proliferation, apoptosis, differentiation and polarization, and cytokine secretion. Their interactions significantly influence lung inflammatory diseases and could be potential therapeutic targets.

Objectives

The review aims to elucidate the role of ncRNAs, especially the interactions between lncRNA and miRNA in lung diseases, including acute and chronic lung inflammatory diseases, as well as lung cancer. And provide novel insights into disease mechanisms and potential therapeutic methods.

Meth

SUBMITTER: Li J 

PROVIDER: S-EPMC10777888 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature