Real-World Data Assessing the Impact of Lymphovascular Space Invasion on the Diagnostic Performance of Sentinel Lymph Node Mapping in Endometrial Cancer.

ABSTRACT:

Background

SLN mapping has emerged as a standard of care in endometrial cancer due to its high sensitivity and significant reduction in morbidity. Although lymphovascular space invasion (LVSI) is a known risk factor for lymph node metastasis and recurrence, evidence on the reliability of SLN mapping in LVSI-positive patients is scarce. The aim of this study was to determine the impact of LVSI on the diagnostic performance of SLN mapping.

Methods

This retrospective cohort study included patients with endometrial cancer who underwent primary surgical treatment at the Bern University Hospital, Switzerland, between 2012 and 2022.

Results

LVSI was present in 22% of patients and was significantly associated with lymph node metastasis (p < 0.001) and recurrence (p<

SUBMITTER: Buechi CA 

PROVIDER: S-EPMC10778553 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature