Sentinel Lymph Node Staging in Early-Stage Cervical Cancer: A Comprehensive Review.

ABSTRACT: Cervical cancer (CC) continues to be a significant global public health concern, even with preventive measures in place. In women with early-stage CC, the status of lymph nodes is of paramount importance, not only for the final prognosis but also for determining the best therapeutic strategy. According to main international guidelines, pelvic full lymphadenectomy (PLND) is recommended for lymph node staging. However, in these early stages of CC, sentinel lymph node biopsy (SLNB) has emerged as a precise technique for evaluating lymph node involvement, improving its morbidity profile. We performed a literature review through PubMed articles about progress on the application of SLNB in women with early-stage CC focusing on the comparison with PET/CT and PLND in terms of oncological outcomes

SUBMITTER: Margioula-Siarkou C 

PROVIDER: S-EPMC10779478 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature