Human robotic surgery with intraoperative tissue identification using rapid evaporation ionisation mass spectrometry.

ABSTRACT: Instantaneous, continuous, and reliable information on the molecular biology of surgical target tissue could significantly contribute to the precision, safety, and speed of the intervention. In this work, we introduced a methodology for chemical tissue identification in robotic surgery using rapid evaporative ionisation mass spectrometry. We developed a surgical aerosol evacuation system that is compatible with a robotic platform enabling consistent intraoperative sample collection and assessed the feasibility of this platform during head and neck surgical cases, using two different surgical energy devices. Our data showed specific, characteristic lipid profiles associated with the tissue type including various ceramides, glycerophospholipids, and glycerolipids, as well as different ion fo

SUBMITTER: Manoli E 

PROVIDER: S-EPMC10781715 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature