Influence of Gender on Tau Precipitation in Alzheimer's Disease According to ATN Research Framework.

ABSTRACT: Tau proteins accumulation and their spreading pattern were affected by gender in cognitive impairment patients, especially in the progression of Alzheimer's disease (AD). However, it was unclear whether the gender effects for tau deposition influenced by amyloid deposition. The aim of this study was to investigate gender differences for tau depositions in Aβ positive (A⁺) subjects. In this study, tau and amyloid positron emission tomography images, structural magnetic resonance imaging images, and demographic information were collected from 179 subjects in Alzheimer's Disease Neuroimaging Initiative (ADNI) database and 63 subjects from Huashan Hospital. Subjects were classified as T⁺ or T^- according to the presence or absence of tau (T) biomarkers. We used

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC10781910 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature