Impact of implementing Dutch versus European guideline risk factor targets in older patients with ischaemic heart disease.

ABSTRACT:

Background

In patients with ischaemic heart disease (IHD) aged > 70 years, Dutch and European guidelines recommend different treatment targets: low-density lipoprotein cholesterol (LDL-c) < 2.6 versus < 1.4 mmol/l and systolic blood pressure (SBP) < 140 versus < 130 mm Hg, respectively. How this impacts cardiovascular event-free life expectancy has not been investigated. The study objective was to compare estimated lifelong treatment benefits of implementing Dutch and European LDL‑c and SBP targets.

Methods

Data from patients aged 71-80 years hospitalised for IHD in 2017-2019 were extracted from the PHARMO Database Network, which links primary and secondary healthcare settings, with follow-up until 31 December 2020. Potential benefit according to treatment strategy (in gain

SUBMITTER: van Trier TJ 

PROVIDER: S-EPMC10781920 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature