Responses to Many Anti-Aging Interventions Are Sexually Dimorphic.

ABSTRACT: There is increasing appreciation that sex differences are not limited to reproductive organs or traits related to reproduction and that sex is an important biological variable in most characteristics of a living organism. The biological process of aging and aging-related traits are no exception and exhibit numerous, often major, sex differences. This article explores one aspect of these differences, namely sex differences in the responses to anti-aging interventions. Aging can be slowed down and/or postponed by a variety of environmental ("lifestyle"), genetic or pharmacological interventions. Although many, particularly older studies utilized only one sex of experimental animals, there is considerable evidence that responses to these interventions can be very different in females and male

SUBMITTER: Bartke A 

PROVIDER: S-EPMC10782120 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature