Medical Treatment for Peyronie's Disease: Systematic Review and Network Bayesian Meta-Analysis.

ABSTRACT:

Purpose

To investigate the efficacy of medical treatment options for Peyronie's disease (PD) including oral drugs, intralesional treatment and mechanical treatment compared with placebo treatment using network meta-analysis (NMA).

Materials and methods

We searched the randomized controlled trials (RCTs) of PD in PubMed, Cochrane library, and EMBASE up to October 2022. RCTs included medical treatment options: oral drugs, intralesional treatment and mechanical treatment. Studies reporting at least one of the outcome measures of interest including curvature degree, plaque size, and structured questionnaires (International Index of Erectile Function, IIEF) were included.

Results

Finally, 24 studies including 1,643 participants met our selection criteria for NMA. There was

SUBMITTER: Lee HY 

PROVIDER: S-EPMC10782133 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature