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ABSTRACT: Background
Differentiation between adenomas and carcinomas of the ampulla of Vater is crucial for therapy and prognosis. This was a systematic review of the literature on the accuracy of diagnostic modalities used to differentiate between benign and malignant ampullary tumours.Methods
A literature search was conducted in PubMed, Embase, CINAHL, and the Cochrane Library. Studies were included if they reported diagnostic test accuracy information among benign and malignant ampullary tumours, and used pathological diagnosis as the reference standard. Risk of bias was assessed using Quality Assessment on Diagnostic Accuracy Studies (QUADAS) 2 and QUADAS-C.Results
Ten studies comprising 397 patients were included. Frequently studied modalities were (CT; 2 studies), endos
SUBMITTER: de Wilde AJ
PROVIDER: S-EPMC10782211 | biostudies-literature | 2024 Jan
REPOSITORIES: biostudies-literature