Early bone loss in patients with obstructive sleep apnea: a cross-sectional study.

ABSTRACT:

Background

Obstructive sleep apnea (OSA) and osteoporosis are both prevalent diseases with shared pathophysiological mechanisms and risk factors. However, the association between the two diseases is seldom studied. This study aimed to identify the link between OSA and bone metabolism.

Methods

Male participants aged 30-59-years who visited the sleep clinic were continuously recruited. Polysomnography was used to evaluate sleep and respiratory conditions. Blood samples were collected to detect metabolic, inflammatory and bone turnover indicators. High-resolution peripheral quantitative computer tomography was used to measure the non-dominant lateral radius and tibia.

Results

Ninety subjects were recruited. The cortical area (Ct.Ar) of tibia of the severe OSA group was s

SUBMITTER: Qiao Y 

PROVIDER: S-EPMC10782667 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature